1-13C-D-Phenylalanine

1-13C-D-Phenylalanine is a stable isotopically labeled form of the amino acid phenylalanine. It is used for a variety of research purposes, including protein structure determination, metabolic pathway analysis, and stable isotope labeling of proteins for quantitative proteomics studies. The carbon-13 isotope in 1-13C-D-Phenylalanine allows for precise measurement of metabolic pathways in cells and organisms. By tracking the movement of labeled carbons through various metabolic intermediates, researchers can gain insight into the biochemical processes involved in protein synthesis and degradation, energy metabolism, and other cellular functions. In addition to its research applications, 1-13C-D-Phenylalanine has potential clinical uses as well. Phenylalanine is an essential amino acid that is converted to tyrosine in the body. Tyrosine is then used to produce neurotransmitters such as dopamine, epinephrine, and norepinephrine. Disorders of phenylalanine metabolism, such as phenylketonuria (PKU), can lead to cognitive impairment and other neurological problems. By studying the metabolism of labeled phenylalanine, researchers may be able to develop new treatments for these and other disorders. Overall, 1-13C-D-Phenylalanine is a valuable tool for researchers and clinicians alike, providing insight into the complex biochemical processes that underlie cellular function and disease.