2-N-Propyl Pramipexole-d4

2-N-Propyl Pramipexole-d4 is a deuterated analogue of Pramipexole, which is a dopamine receptor agonist used for the treatment of Parkinson's disease and Restless Leg Syndrome. Deuterated compounds are chemically similar to their non-deuterated counterparts, but with one or more hydrogen atoms replaced with deuterium. These deuterium atoms improve the pharmacokinetic properties of the drug, such as increasing its metabolic stability, reducing toxicity, and improving its bioavailability. The chemical formula of 2-N-Propyl Pramipexole-d4 is C10H15D4N3 and its molecular weight is 192.31 g/mol. It is a white to off-white powder that is soluble in water and organic solvents like methanol and ethanol. The compound is stable under normal conditions and can be stored at room temperature. In terms of usage, 2-N-Propyl Pramipexole-d4 is used as an internal standard in pharmacokinetic studies of Pramipexole. It is added to biological samples in known amounts before analysis by liquid chromatography-mass spectrometry (LC-MS) to accurately quantify the concentration of Pramipexole in the sample. This is important for determining the drug's efficacy and safety in patients. Overall, 2-N-Propyl Pramipexole-d4 is a useful tool for pharmacokinetic studies of Pramipexole, as its deuterated form improves the accuracy and precision of analysis.