Rifampicin-d3

Product Name Rifampicin-d3
Alternate Names Rifampicin Stable Isotopes, Stable Isotopes of Rifampicin
CAT No. CS-T-86068
CAS No. 1262052-36-7
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 825.96 g/mol
Mol. For. C₄₃H₅₅D₃N₄O₁₂
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Rifampicin
Canonical Smiles CC1C=CC=C(C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C=NN5CCN(CC5)C)C
InchIKey JQXXHWHPUNPDRT-LGNOTXDQSA-N
Inchl InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/t21-,23-,24+,25+,29-,34-,35+,39+,43-/m0/s1/i9D3
IUPAC [(7S,11S,12S,13S,14R,15R,16R,17S,18S)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-26-[[4-(trideuteriomethyl)piperazin-1-yl]iminomethyl]-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate
Controlled No
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Rifampicin-d3 is a deuterated form of the antibiotic Rifampicin. It is used to treat bacterial infections such as tuberculosis and leprosy. Rifampicin-d3 works by inhibiting the bacterial RNA polymerase enzyme, which is responsible for the transcription of DNA into RNA. This inhibition leads to the prevention of protein synthesis and ultimately, bacterial cell death. Chemically, Rifampicin-d3 is a macrocyclic antibiotic with a complex structure that includes a naphthoquinone moiety. It is soluble in organic solvents such as chloroform and methanol but is sparingly soluble in water. Rifampicin-d3 has a molecular weight of 822.02 g/mol and a melting point of 183-186°C. The recommended dosage of Rifampicin-d3 varies depending on the severity and type of infection being treated. It is usually administered orally, with or without food, and is metabolized in the liver and excreted in the urine. Rifampicin-d3 may interact with other medications, so it is important to inform your healthcare provider of any other drugs you are taking. Like other antibiotics, Rifampicin-d3 may cause side effects such as nausea, vomiting, and diarrhea. It may also cause liver damage, so regular monitoring of liver function is recommended during treatment. Overall, Rifampicin-d3 is an effective and important medication in the treatment of bacterial infections, but should only be used under the guidance of a healthcare professional.

Related Compounds

N-Desmethyl N-Nitroso Rifampicin-D8 | Rifampicin D8 | Rifampicin N-Oxide-D8 | Rifampicin D4 |

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