Product Name |
(S)-(-)-Verapamil-d3 Hydrochloride |
Alternate Names |
Verapamil Stable Isotopes, Stable Isotopes of Verapamil |
CAT No. |
CS-T-87828
|
CAS No. |
1398112-33-8 |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
Not Available |
Mol. For. |
Not Available
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Verapamil |
Therapeutic |
Anti-Migraines |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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(S)-(-)-Verapamil-d3 Hydrochloride is a deuterated form of (S)-(-)-Verapamil Hydrochloride, which is a calcium channel blocker used in the treatment of hypertension, angina pectoris, and arrhythmia. The deuterated form is used in pharmacokinetic and metabolic studies to determine the fate of the drug in vivo.
The chemical formula of (S)-(-)-Verapamil-d3 Hydrochloride is C27H31D3ClN2O4, and its molecular weight is 487.08 g/mol. The compound is a white to off-white crystalline powder that is soluble in water, ethanol, and methanol. It has a melting point of 140-142°C.
The mechanism of action of (S)-(-)-Verapamil-d3 Hydrochloride involves blocking the inward movement of calcium ions through the cell membrane, which reduces the contractility of the heart muscle and dilates the peripheral blood vessels. This results in reduced blood pressure and improved blood flow to the heart and other organs.
In pharmacokinetic studies, (S)-(-)-Verapamil-d3 Hydrochloride is administered orally or intravenously to human or animal subjects, and its plasma concentration and metabolic products are measured over time. The deuterated form allows for accurate quantification of the drug and its metabolites using mass spectrometry.
In conclusion, (S)-(-)-Verapamil-d3 Hydrochloride is a useful tool for pharmacokinetic and metabolic studies of (S)-(-)-Verapamil Hydrochloride, a commonly used calcium channel blocker. Its chemical and pharmacological properties make it a valuable resource for researchers and clinicians seeking to better understand the pharmacokinetics of this drug and its therapeutic effects.