N-Desmethyl Imatinib Mesylate
| Product Name | N-Desmethyl Imatinib Mesylate |
|---|---|
| Alternate Names | Imatinib Impurities, Impurities of Imatinib |
| CAT No. | CS-T-88207 |
| CAS No. | 404844-03-7 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 575.68 g/mol |
| Mol. For. | C₂₉H₃₃N₇O₄S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Imatinib |
| Smileys | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCNCC3)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
| Canonical Smiles | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCNCC3)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
| InchIKey | BRTOZFXRYMYSOF-UHFFFAOYSA-N |
| Inchl | InChI=1S/C28H29N7O.CH4O3S/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35;1-5(2,3)4/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34);1H3,(H,2,3,4) |
| IUPAC | methanesulfonic acid;N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Desmethyl Imatinib Mesylate is a chemical compound used in the treatment of certain types of cancer. It is a metabolite of Imatinib Mesylate, which is commonly used to treat chronic myeloid leukemia and gastrointestinal stromal tumors. N-Desmethyl Imatinib Mesylate is formed in the liver when Imatinib Mesylate is metabolized.
The chemical formula of N-Desmethyl Imatinib Mesylate is C27H29N7O2S, and its molecular weight is 523.64 g/mol. It is a white to off-white powder that is soluble in water and dimethyl sulfoxide.
In terms of its mechanism of action, N-Desmethyl Imatinib Mesylate works by inhibiting the tyrosine kinase activity of certain proteins, including BCR-ABL, c-KIT, and PDGFR. This prevents the growth and proliferation of cancer cells, leading to tumor regression.
N-Desmethyl Imatinib Mesylate is usually administered orally in the form of tablets. The recommended dose varies depending on the type and stage of cancer being treated. It is important to follow the dosage instructions provided by the healthcare provider.
Like any other medication, N-Desmethyl Imatinib Mesylate may cause side effects, such as fatigue, nausea, diarrhea, and skin rash. It may also interact with other medications, so it is important to inform the healthcare provider of any other drugs being taken. Overall, N-Desmethyl Imatinib Mesylate is an important drug in the treatment of certain types of cancer, and its usage should be carefully monitored by a healthcare professional.
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Related Compounds
Imatinib Hydrochloride Impurity G | Imatinib (Pyridine)-N-oxide | Imatinib (Piperazine)-N4-Oxide | Imatinib N-Acetyl Impurity | Imatinib Dimethylamino Impurity | Imatinib Impurity B | N-Boc-N-Desmethyl Imatinib | N-Desmethyl -N-Nitroso Imatinib | Imatinib (N-nitroso benzamide) | Imatinib Dimer | N-(3-methyl5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4((4-methylpiperazin-1-yl)methyl)benz | Fluorescent derivative of imatinib | N-Nitroso Imatinib impurity F | Imatinib Impurity 3 | Imatinib N-Desmethyl Impurity | Imatinib EP Impurity D Tetrahydrochloride | N-(2-Methyl-5-nitrophenyl)-4-(pyridine-3-yl)pyridine-2-amine | Imatinib Guanidino Dihydrochloride Impurity | Imatinib Impurity 16 | N-Nitroso Imatinib | N-Desmethyl -n-nitroso imatinib 1 | Imatinib EP Impurity C Trihydrochloride | Imatinib Impurity 5 | Imatinib EP Impurity C | Imatinib EP Impurity D | N-Nitroso Imatinib Nitro Intermediate | N-Nitroso Imatinib guanidine Intermediate | Des-4-methylpiperazin chloro Imatinib impurity | Imatinib Imidazole Impurity | Imatinib N-Formyl Impurity | Imatinib impurity B | Imatinib EP Impurity D (chloride) | Imatinib DiPiperazine Impurity |