2-[(Diethylamino)methyl]-4-nitrophenol-d10

2-[(Diethylamino)methyl]-4-nitrophenol-d10 is a deuterated derivative of 2-[(Diethylamino)methyl]-4-nitrophenol, a synthetic compound commonly used in the research and development of pharmaceuticals. It is a stable isotopic chemical, with 10 deuterium atoms replacing 10 hydrogen atoms, and is used primarily in the field of drug metabolism and pharmacokinetics. The compound is used as a stable isotope labeled internal standard in drug metabolism studies, where it is added to biological samples to monitor the metabolism and pharmacokinetics of pharmaceutical drugs. It is also used as a reference standard in analytical chemistry and in the development of analytical methods for the quantification of drugs in biological samples. Chemically, 2-[(Diethylamino)methyl]-4-nitrophenol-d10 is a yellow crystalline powder with a molecular weight of 249.32 g/mol. It has a melting point of 122-126 °C and is soluble in organic solvents such as methanol and acetonitrile. The compound is classified as a tertiary amine, with a nitro group and a phenolic hydroxyl group attached to the aromatic ring. It has a pKa value of 4.75, indicating its acidic nature, and is known to undergo biotransformation in the liver via hydroxylation and glucuronidation pathways. Overall, 2-[(Diethylamino)methyl]-4-nitrophenol-d10 is a valuable tool in the field of drug metabolism and pharmacokinetics, offering precise and accurate measurements of drug metabolism and pharmacokinetic parameters.