(4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3

(4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3 is a deuterated form of the antifungal drug linezolid, which is used to treat bacterial infections caused by gram-positive bacteria. This compound is labeled with stable isotopes of hydrogen, specifically deuterium (^2H), which allows for its use in quantitative studies and pharmacokinetic research. The chemical formula of this compound is C16H13D3F2N4O3, and its molecular weight is 344.4 g/mol. It is a white to off-white crystalline powder, and it is soluble in acetonitrile, methanol, and dimethyl sulfoxide. (4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3 works by inhibiting the bacterial protein synthesis process, specifically by binding to the 23S ribosomal RNA of the bacterial ribosome. This leads to the inhibition of bacterial growth and the treatment of infections caused by gram-positive bacteria. In conclusion, (4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3 is a deuterated form of the antifungal drug linezolid, used in pharmacokinetic and quantitative studies. Its chemical formula, molecular weight, and solubility properties make it a useful tool in research. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 23S ribosomal RNA of the bacterial ribosome.