17β-Estradiol-13C2

17β-Estradiol-13C2 is a stable isotope-labeled analog of the naturally occurring estrogen hormone, 17β-estradiol. It is primarily used in research and clinical applications to study the metabolism, distribution, and excretion of endogenous estrogen in the human body. The incorporation of stable carbon-13 isotopes into the molecular structure of 17β-estradiol-13C2 allows for precise and accurate monitoring of the hormone's behavior in vivo, without interfering with its biological activity. Chemically, 17β-Estradiol-13C2 is a steroid hormone that belongs to the class of estrogen hormones, which are primarily responsible for the development and maintenance of female reproductive tissues and secondary sex characteristics. The hormone is synthesized from cholesterol in the ovaries and adrenal glands, and plays a critical role in the regulation of the menstrual cycle, pregnancy, and bone density. In clinical settings, 17β-Estradiol-13C2 is commonly used in tracer studies to evaluate the pharmacokinetics of estrogen-based therapies and to determine the effectiveness of various treatments. The hormone is also used in research applications to study the molecular mechanisms of estrogen signaling and its role in the development and progression of breast cancer and other hormone-dependent diseases. In summary, 17β-Estradiol-13C2 is a valuable research tool that provides insights into the complex biological processes associated with estrogen metabolism and signaling. Its use in clinical and research applications has contributed significantly to our understanding of the role of estrogen in human health and disease.