Vardenafil N-Oxide

Product Name Vardenafil N-Oxide
CAT No. CS-T-93343
CAS No. 448184-48-3
Category Impurities
Stock IN-Stock
Mol. Wt. 504.60 g/mol
Mol. For. C₂₃H₃₂N₆O₅S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Purity 95%
Therapeutic Erectile dysfunction
Smileys CCOC1=C(C(NN2C3=C(C)N=C2CCC)=NC3=O)C=C([S](=O)(N4CC[N+](CC)([O-])CC4)=O)C=C1
Canonical Smiles CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CC[N+](CC4)(CC)[O-])OCC)C
InchIKey GXUGEZIHENHAGP-UHFFFAOYSA-N
Inchl InChI=1S/C23H32N6O5S/c1-5-8-20-24-16(4)21-23(30)25-22(26-28(20)21)18-15-17(9-10-19(18)34-7-3)35(32,33)27-11-13-29(31,6-2)14-12-27/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30)
IUPAC 2-[2-ethoxy-5-(4-ethyl-4-oxidopiperazin-4-ium-1-yl)sulfonylphenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
Controlled No
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Vardenafil N-Oxide is a synthetic compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, which are commonly used for the treatment of erectile dysfunction (ED). This compound is a derivative of vardenafil, a FDA-approved drug for the treatment of ED. Vardenafil N-Oxide is a potent inhibitor of PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By inhibiting PDE5, vardenafil N-Oxide increases the concentration of cGMP, which leads to smooth muscle relaxation and increased blood flow to the penis, resulting in an erection. The chemical formula of Vardenafil N-Oxide is C23H32N6O4S, and its molar mass is 492.61 g/mol. Vardenafil N-Oxide is a white to off-white crystalline powder that is soluble in water, ethanol, and methanol. This compound has a melting point of 170°C to 175°C. In terms of usage, Vardenafil N-Oxide is still in the experimental stage and has not been approved for clinical use. However, studies have shown that this compound has a higher potency and a longer half-life than vardenafil. Vardenafil N-Oxide has also shown promising results in animal studies as a potential treatment for ED. Further studies are needed to determine the safety and efficacy of Vardenafil N-Oxide in humans.

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