3-Hydroxy Midostaurin-13C6
| Product Name | 3-Hydroxy Midostaurin-13C6 |
|---|---|
| Alternate Names | Midostaurin Stable Isotopes, Stable Isotopes of Midostaurin |
| CAT No. | CS-T-93594 |
| CAS No. | 179237-49-1 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 592.59 mol/g g/mol |
| Mol. For. | C₂₉¹³C₆H₃₀N₄O₅ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Midostaurin |
| Canonical Smiles | CC1=CC2=C(C=C1)N=C(N2)C |
| InchIKey | MVHOAOSHABGEFL-UHFFFAOYSA-N |
| Inchl | InChI=1S/C9H10N2/c1-6-3-4-8-9(5-6)11-7(2)10-8/h3-5H,1-2H3,(H,10,11) |
| IUPAC | 2,6-dimethyl-1H-benzimidazole |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3-Hydroxy Midostaurin-13C6 is a stable isotope-labeled derivative of the drug Midostaurin, also known as PKC412. Midostaurin is a multi-kinase inhibitor that has shown promising results in the treatment of acute myeloid leukemia, systemic mastocytosis, and advanced gastrointestinal stromal tumors.
The 13C6 labeling of 3-Hydroxy Midostaurin allows for precise analysis of the drug in biological samples and enables researchers to determine the pharmacokinetic and pharmacodynamic properties of Midostaurin. This stable isotope-labeled compound has been used in preclinical and clinical studies to investigate the metabolism, distribution, and excretion of Midostaurin.
3-Hydroxy Midostaurin-13C6 is a potent inhibitor of protein kinase C (PKC) and other receptor tyrosine kinases. It works by preventing the activation of these kinases, which are involved in cell growth, differentiation, and survival. This inhibition leads to the induction of apoptosis, or programmed cell death, in cancer cells.
The chemical formula of 3-Hydroxy Midostaurin-13C6 is C33H30D6N7O4, with a molecular weight of 597.7 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide (DMSO) and ethanol.
In conclusion, 3-Hydroxy Midostaurin-13C6 is a useful tool for researchers studying the pharmacology and mechanism of action of Midostaurin. Its stable isotope labeling allows for accurate analysis of the drug in biological samples and contributes to the development of new treatments for cancer and other diseases.
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Related Compounds
Midostaurin metabolite-13C6 (CGP52421) | O-Desmethyl Midostaurin-13C6 | Midostaurin 13C6 | O-Desmethyl Midostaurin D5 | Midostaurin D5 |