Aripiprazole-d8 (piperazine-d8)

Chemical Name Aripiprazole-d8 (piperazine-d8)
Alternate Names Aripiprazole Stable Isotopes, Stable Isotopes of Aripiprazole
CAT No. CS-T-93678
CAS Registry# 1089115-06-9
Category Stable Isotopes
Stock Enquire
Mol. Wt. 456.43 g/mol
Mol. For. C23H19D8Cl2N3O2
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Aripiprazole
Smileys O=C1NC2=C(C=CC(OCCCCN3C([2H])([2H])C([2H])([2H])N(C4=CC=CC(Cl)=C4Cl)C([2H])([2H])C3([2H])[2H])=C2)CC1
Canonical Smiles C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
InchIKey CEUORZQYGODEFX-FUEQIQQISA-N
Inchl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)/i11D2,12D2,13D2,14D2
IUPAC 7-[4-[2,2,3,3,5,5,6,6-octadeuterio-4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Controlled No
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Aripiprazole-d8 (piperazine-d8) is a deuterated derivative of Aripiprazole, which is a second-generation antipsychotic medication used to treat various mental health disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Aripiprazole works by rebalancing the levels of certain chemicals in the brain, including dopamine and serotonin. Aripiprazole-d8 (piperazine-d8) is used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of Aripiprazole in the human body. Deuterated compounds like Aripiprazole-d8 (piperazine-d8) are used in these studies because they have similar chemical and physical properties to the non-deuterated compounds, but can be easily distinguished and measured using mass spectrometry. Chemically, Aripiprazole-d8 (piperazine-d8) is a deuterated form of Aripiprazole that contains eight deuterium atoms in the piperazine ring. Deuterium is a stable isotope of hydrogen that has one extra neutron in its nucleus, giving it a slightly higher atomic mass. This small difference in mass allows Aripiprazole-d8 (piperazine-d8) to be distinguished from the non-deuterated Aripiprazole using mass spectrometry. In summary, Aripiprazole-d8 (piperazine-d8) is a deuterated derivative of Aripiprazole that is used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of Aripiprazole in the human body. Its chemical properties make it a useful tool in these studies and it is commonly used by researchers and pharmaceutical companies to better understand how Aripiprazole works in the body.

Related Compounds

Aripiprazole (D8) | Dehydro Aripiprazole D8 (piperazine-d8) | Aripiprazole-d8 (butyl-d8) |

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