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Amifostine Thiol Dihydrochloride-d4

Product Information

Product Amifostine Thiol Dihydrochloride-d4
CAT No. CS-T-93898
CAS No. 14653-77-1 (Unlabelled)
Status price
Category Stable Isotopes
Mol. Wt. 211.19 mol/g
Mol. For. C5H12D4Cl2N2S
Hazardous This is not a Hazardous Compound

Product Description

Amifostine Thiol Dihydrochloride-d4 is a deuterated analogue of Amifostine Thiol Dihydrochloride, which is an organic compound used in the treatment of cancer. It is a prodrug that is dephosphorylated by alkaline phosphatase to its active form, which acts as a potent cytoprotective agent. This compound is a potent scavenger of reactive oxygen species, which are known to cause cellular damage, and it has been shown to protect normal tissues from the harmful effects of radiation and chemotherapy. Amifostine Thiol Dihydrochloride-d4 is used in various research studies where the use of a deuterated analogue is required. It is a useful tool for pharmacokinetic studies, as it allows the tracking of the compound’s metabolism and distribution in vivo. The deuterated analogue also has a unique mass spectral signature, which can be used to distinguish it from the non-deuterated compound in biological samples. Chemically, Amifostine Thiol Dihydrochloride-d4 is a white crystalline powder with a molecular weight of 248.24 g/mol and a chemical formula of C5H10D4Cl2NOS. It is soluble in water and methanol, and it has a melting point of 245-247°C. This compound is stable under normal conditions of use and storage, and it should be stored in a dry and cool place. It is important to handle this compound with care, as it is a toxic and irritant substance.

Additional Information

Packing Product will be supplied in Vials, in certain conditions we also use 'Septa Vials'
Controlled No
Parent API Amifostine
Canonical Smiles C(CN)CNCCS.Cl.Cl
Inchl InChI=1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
IUPAC 2-(3-aminopropylamino)ethanethiol;dihydrochloride
Hazardous No

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Safety & Handling Information

General Information Use proper personal protective equipment
Handling Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Engineering Control Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Clothing Wear appropriate protective clothing to minimize contact with skin.
Skin Wear appropriate protective gloves and clothing to prevent skin exposure.
Eyes Wear safety glasses and chemical goggles if splashing is possible.
Inhalation Remove from exposure and move to fresh air immediately.

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Sample Label

logo Amifostine Thiol Dih... www.clearsynth.com 
 CAT : CS-T-93898 BATCH : CSC-WWW0757

 MF: C5H12D4Cl2N2S
 CAS: 14653-77-1 (Unlabelled)
 Date of Anaysis: 22-Aug-2023
 Retest Date: 22-Jun-2026
MW: 211.19

Store at refrigerator (2-8C)
Qty: 60 MG 
 Only for R & D and Analytical purpose, Not for Human Consumption.

Sample Packaging

Sample Packaging

Sample Vials

Sample Vials
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