3'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt

Product Name 3'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt
CAT No. CS-T-93947
CAS No. 133525-01-6 (unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 468.37 g/mol
Mol. For. C₁₆H₁₇D₃N₅NaO₁₀
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Canonical Smiles CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC3C(C(C(C(O3)C(=O)[O-])O)O)O)N=[N+]=[N-].[Na+]
InchIKey ANFPIJBVCFGZOF-VDDYBQMTSA-M
Inchl InChI=1S/C16H21N5O10.Na/c1-5-3-21(16(28)18-13(5)25)8-2-6(19-20-17)7(30-8)4-29-15-11(24)9(22)10(23)12(31-15)14(26)27;/h3,6-12,15,22-24H,2,4H2,1H3,(H,26,27)(H,18,25,28);/q;+1/p-1/t6-,7-,8-,9+,10+,11+,12?,15-;/m1./s1
IUPAC sodium;(3S,4S,5S,6R)-6-[[(2S,3R,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylate
Controlled No
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3'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt is a chemical compound that is commonly used in research studies and medical laboratories. This compound is a derivative of the antiviral drug, Zidovudine or AZT, which is used in the treatment of HIV infection. The addition of a glucuronide group to AZT enhances its pharmacokinetic profile, making it more soluble in water and improving its bioavailability. The compound is a white powder with a molecular formula of C17H20N5O8S and a molecular weight of 476.44 g/mol. It is a stable and non-toxic compound that can be stored at room temperature. The sodium salt form of the compound makes it more water-soluble, which is important for its use in biological assays. In research studies, 3'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt is used as a tracer molecule to study drug metabolism and pharmacokinetics. It is also used as a reference standard for the quantification of AZT glucuronides in biological samples. The compound can be administered to animals or added to in vitro cultures to study its effects on cellular processes. Overall, 3'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt is a valuable tool for researchers investigating drug metabolism and pharmacokinetics, as well as those studying the mechanisms of antiviral drugs.

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