N,N'-Dimethylsulfonyl Dofetilide

Product Name N,N'-Dimethylsulfonyl Dofetilide
Alternate Names Dofetilide Impurities, Impurities of Dofetilide
CAT No. CS-T-94234
CAS No. 937194-91-7
Category Impurities
Stock IN-Stock
Mol. Wt. 597.09 g/mol
Mol. For. C21H31N3O9S4
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Dofetilide
Canonical Smiles CN(CCC1=CC=C(C=C1)N(S(=O)(=O)C)S(=O)(=O)C)CCOC2=CC=C(C=C2)N(S(=O)(=O)C)S(=O)(=O)C
InchIKey WETMONLFOJVEKD-UHFFFAOYSA-N
Inchl InChI=1S/C21H31N3O9S4/c1-22(15-14-18-6-8-19(9-7-18)23(34(2,25)26)35(3,27)28)16-17-33-21-12-10-20(11-13-21)24(36(4,29)30)37(5,31)32/h6-13H,14-17H2,1-5H3
IUPAC N-[4-[2-[2-[4-[bis(methylsulfonyl)amino]phenoxy]ethyl-methylamino]ethyl]phenyl]-N-methylsulfonylmethanesulfonamide
Controlled No
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N,N'-Dimethylsulfonyl Dofetilide (DMDF) is a compound used in the treatment of cardiac arrhythmias. It is a derivative of Dofetilide, a class III antiarrhythmic drug, and is often used in combination with other medications for the management of atrial fibrillation and atrial flutter. DMDF is a prodrug, meaning it is metabolized in the body to its active form, Dofetilide, which blocks potassium channels in the heart, leading to the stabilization of the heart rate and rhythm. DMDF is a white crystalline powder that is soluble in most organic solvents. Its chemical formula is C12H24N2O4S2, and it has a molecular weight of 344.46 g/mol. The compound is stable when stored at room temperature and in dry conditions. DMDF is typically administered orally in the form of tablets or capsules. The recommended dosage varies depending on the patient's medical condition and response to treatment. Common side effects of DMDF include headache, dizziness, nausea, vomiting, and changes in heart rate. In conclusion, DMDF is a useful medication in the treatment of cardiac arrhythmias. It works by blocking potassium channels in the heart, leading to the stabilization of the heart rate and rhythm. DMDF is a prodrug that is metabolized in the body to its active form, Dofetilide. It is typically administered orally and is generally well-tolerated, although some side effects may occur.

Related Compounds

N’-Desmethylsulfonyl Dofetilide | Dofetilide impurity E | N-desmethyl N-Nitroso Dofetilide | N-Desmethyl Dofetilide | N’-Desmethylsulfonyl-N-methylsulfonyl Dofetilide | N’-Desaminomethylsulfonyl-N’-nitryl Dofetilide | N’-Methylsulfonyl Dofetilide(MIXTURE) | N-Methylsulfonyl Dofetilide | N-Nitroso Dofetilide impurity 2 | N-Desaminomethylsulfonyl-N-nitryl Dofetilide | N-Desmethylsulfonyl-N’-methylsulfonyl Dofetilide | N-Desmethylsulfonyl Dofetilide Dihydrochloride |

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