7,8-Didehydro-10-hydroxy-naloxone
| Product Name | 7,8-Didehydro-10-hydroxy-naloxone |
|---|---|
| Alternate Names | Naloxon Impurities, Impurities of Naloxon |
| CAT No. | CS-T-94248 |
| CAS No. | Not Available |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 341.36 g/mol |
| Mol. For. | C₁₉H₁₉NO₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Naloxon |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
7,8-Didehydro-10-hydroxy-naloxone (DDHN) is a synthetic compound that acts as an opioid antagonist. It is a derivative of naloxone, a medication commonly used to reverse the effects of opioid overdose. DDHN has been shown to have a higher binding affinity for the mu-opioid receptor than naloxone, making it a more potent antagonist.
DDHN has potential use in the treatment of opioid addiction and overdose. It has been shown to reduce the rewarding effects of opioids, which can help prevent relapse in individuals in recovery. Additionally, it has been found to be effective in reversing respiratory depression caused by opioid overdose, which is the leading cause of death in opioid overdose cases.
Chemically, DDHN is a derivative of naloxone and has a molecular weight of 327.4 g/mol. Its chemical formula is C19H19NO4 and it has a melting point of 210-212°C. It is a pale yellow powder that is soluble in ethanol, acetone, and dimethyl sulfoxide (DMSO).
In conclusion, DDHN is a promising compound for the treatment of opioid addiction and overdose. Its high binding affinity for the mu-opioid receptor and ability to reduce the rewarding effects of opioids make it a potent antagonist. Further research is needed to fully understand its potential therapeutic applications and any potential side effects.
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Related Compounds
Naloxone EP Impurity B | Naloxone EP Impurity G | Naloxone Benzoylhydrazone | Naloxone Amide | Naloxone EP Impurity F | Naloxone impurity at RRT 0.371 | Naloxone EP Impurity A | Naloxone EP Impurity I | Naloxone Hydrochloride - Impurity G | Naloxone Impurity 2 | Naloxone Impurity 3 | Naloxone impurity at RRT 0.594 | Naloxone impurity at RRT 0.555 | Naloxone EP Impurity C | O-propyl Naloxone enol ether | Naloxone EP Impurity D | Naloxone Hydroxylamine | Naloxone Impurity 1 |