1-Oxo Fexofenadine-d10 Methyl Ester

1-Oxo Fexofenadine-d10 Methyl Ester is a deuterated form of Fexofenadine, which is an antihistamine medication used to treat various allergic conditions such as hay fever, hives, and allergic skin reactions. This deuterated form of Fexofenadine is used in biochemical and biomedical research as a stable isotope-labeled internal standard for the quantification of Fexofenadine in biological matrices using mass spectrometry. The chemical name of 1-Oxo Fexofenadine-d10 Methyl Ester is (R)-4'-Hydroxy-3'-[(1-oxo-2-methylpropyl)-d10]methyl]-N-[2-[4-(hydroxydiphenylmethyl)-1-piperidinyl]ethyl]-benzeneacetamide. It has a molecular weight of 466.58 g/mol with a chemical formula of C28H29D10NO3. The deuterated form of Fexofenadine is synthesized by introducing deuterium atoms into the molecule, which increases its stability and makes it useful as an internal standard in mass spectrometry-based quantification methods. This labeling technique enables accurate and precise quantification of Fexofenadine in biological matrices such as plasma, urine, and tissues. In conclusion, 1-Oxo Fexofenadine-d10 Methyl Ester is a stable isotope-labeled internal standard used in biochemical and biomedical research for the quantification of Fexofenadine in biological matrices using mass spectrometry. Its chemical properties and stable isotopic labeling make it an important tool in the field of pharmacology and drug discovery.