1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C18

1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine-13C18, also known as POPC-13C18, is a phospholipid molecule that is commonly used in biological research and drug development. It is composed of a glycerol backbone, two fatty acid chains (palmitoyl and oleoyl), a phosphate group, and a choline head group. The 13C18 label indicates that carbon-13 has been incorporated into the fatty acid chains for isotopic labeling studies. POPC-13C18 is often used as a model membrane lipid due to its structural similarity to natural phospholipids. It can be incorporated into liposomes or supported lipid bilayers for use in studies of membrane biophysics, protein-membrane interactions, and drug delivery. POPC-13C18 can also be used in mass spectrometry-based lipidomics to identify and quantify lipid species within biological samples. In terms of chemical information, POPC-13C18 has a molecular weight of 848.12 g/mol and a melting point of approximately 63-65°C. Its solubility in water is low, but it can be dissolved in organic solvents such as chloroform or methanol. The presence of the 13C18 label allows for detection and quantification of the molecule using mass spectrometry techniques. Overall, POPC-13C18 is a valuable tool for investigating the properties and functions of biological membranes.