N-(Nitrosomethyl)ethanolamine

N-(Nitrosomethyl)ethanolamine, commonly referred to as NMEA, is a highly toxic and carcinogenic compound that belongs to the class of nitrosamines. It is a yellowish, oily liquid that has a strong odor and is highly volatile. NMEA is commonly used as a chemical intermediate in the production of various industrial chemicals, such as surfactants, lubricants, and rubber additives. NMEA is formed when ethanolamine reacts with nitrous acid, which is generated in situ from nitrite salts in acidic conditions. NMEA is highly reactive and can form adducts with amino acids and proteins, which can lead to DNA damage and mutations. Exposure to NMEA can have serious health consequences, including the development of cancer, liver damage, and reproductive toxicity. The use of NMEA in industrial processes has been restricted in many countries due to its hazardous properties. However, it can still be found in some consumer products, such as cosmetics and toiletries, as a contaminant. It is important to note that NMEA can be formed in the body from the reaction between nitrite and ethanolamine, which are commonly found in food and beverages. Therefore, it is important to limit the intake of nitrite-containing foods and beverages to reduce the risk of exposure to NMEA.