Amphotericin B Methyl Ester-d3 (>80%)

Amphotericin B Methyl Ester-d3 (>80%) is a deuterated derivative of the antifungal drug Amphotericin B. This compound is used primarily as a research tool for studying the pharmacokinetics and metabolism of Amphotericin B in vivo and in vitro. The deuterium-labeled version of the drug is particularly useful in drug metabolism studies as it allows for the identification and quantification of metabolites by mass spectrometry. Amphotericin B Methyl Ester-d3 (>80%) is a yellow to orange powder that is soluble in organic solvents such as methanol, ethanol, and DMSO. It is stable under normal storage conditions and should be stored in a cool, dry place away from light and moisture. The chemical formula of Amphotericin B Methyl Ester-d3 (>80%) is C47H71NO17 and its molecular weight is 924.08 g/mol. It is a polyene macrolide antibiotic that binds to ergosterol in the fungal cell membrane, leading to membrane disruption and cell death. The deuterium-labeled version of the drug is structurally identical to the unlabeled version, with the exception of three deuterium atoms that have been substituted for hydrogen atoms. In summary, Amphotericin B Methyl Ester-d3 (>80%) is a valuable research tool for studying the pharmacokinetics and metabolism of Amphotericin B. Its deuterium-labeled structure allows for the identification and quantification of metabolites, making it an important compound in drug metabolism studies.