17beta-Estradiol-d3 17-Acetate 3-beta-D-Glucuronide

17beta-Estradiol-d3 17-Acetate 3-beta-D-Glucuronide, also known as E2-d3-Ac-Glu, is a synthetic form of the hormone estrogen. It is a derivative of 17beta-estradiol, which is a naturally occurring hormone in the human body. E2-d3-Ac-Glu is used as a research tool to study the metabolism and elimination of estrogen in the body. The chemical formula for E2-d3-Ac-Glu is C27H31D3O13, and its molecular weight is 605.54 g/mol. The compound is a white to off-white powder that is soluble in water and ethanol. In the body, estrogen plays a critical role in the development and maintenance of female reproductive organs and secondary sex characteristics. E2-d3-Ac-Glu is metabolized in the liver and excreted in the urine as glucuronide conjugates. The glucuronide conjugation of E2-d3-Ac-Glu increases its water solubility and facilitates its elimination from the body. In research settings, E2-d3-Ac-Glu is used to study the pharmacokinetics of estrogen and its metabolites. It is also used to investigate the role of estrogen in various physiological processes, such as bone metabolism, cardiovascular health, and cancer development. E2-d3-Ac-Glu is available from chemical suppliers and can be used in a variety of analytical and biological assays.