(S)-(-)-Nicotine-d3

(S)-(-)-Nicotine-d3 is a stable isotope-labeled form of the alkaloid nicotine, commonly found in tobacco leaves. This compound is used in various scientific studies and research to explore the pharmacology and neurochemistry of nicotine. Nicotine is a highly addictive substance that binds to nicotine receptors in the brain, leading to the release of neurotransmitters such as dopamine, which creates feelings of pleasure and reward. The use of (S)-(-)-Nicotine-d3 allows researchers to track the behavior and metabolism of nicotine in the body through the use of mass spectrometry techniques. Chemically, (S)-(-)-Nicotine-d3 is an isotopically labeled version of the naturally occurring (S)-(-)-nicotine, where three of the hydrogen atoms have been replaced with stable deuterium isotopes. It has a molecular weight of 163.24 g/mol and a melting point of 68-70°C. This compound is soluble in water and organic solvents such as ethanol and chloroform. In addition to its use in research, (S)-(-)-Nicotine-d3 can also be used in the development of new medications for smoking cessation and other nicotine addiction treatments. Its stable isotope labeling provides a valuable tool for drug development as it allows for the accurate measurement of pharmacokinetics and pharmacodynamics of nicotine in the body. Overall, (S)-(-)-Nicotine-d3 is an important compound for understanding the effects of nicotine on the body and developing new treatments for nicotine addiction.