Bumetanide D5

Product Name Bumetanide D5
Alternate Names Bumetanide Stable Isotopes, Stable Isotopes of Bumetanide
CAT No. CS-O-02974
CAS No. 1216739-35-3
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 369.45 g/mol
Mol. For. C₁₇H₁₅D₅N₂O₅S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Bumetanide
Purity Not less than 90 %
Therapeutic Anti-Hypertensives
Smileys [2H]C1=C(C(=C(C(=C1[2H])[2H])OC2=C(C=C(C=C2S(=O)(=O)N)C(=O)O)NCCCC)[2H])[2H]
Controlled No
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Bumetanide D5 is a deuterated version of the diuretic drug Bumetanide, which is primarily used to treat edema caused by congestive heart failure, liver cirrhosis, and kidney disease. Bumetanide D5 is used for the same purpose, but with the added benefit of increased selectivity and potency due to the incorporation of deuterium isotopes. The chemical formula of Bumetanide D5 is C16H13D5N2O5S, and it has a molecular weight of 365.49 g/mol. The drug works by inhibiting the sodium-potassium-chloride cotransporter in the ascending loop of Henle in the kidneys, leading to increased excretion of sodium, potassium, and chloride ions in the urine. This reduces the water retention in the body and helps to reduce swelling and edema. The recommended dosage of Bumetanide D5 is typically 0.5 to 2 mg per day, which can be adjusted based on individual patient response. The drug is administered orally or intravenously and is usually well-tolerated, although some patients may experience side effects such as dizziness, headache, and nausea. In conclusion, Bumetanide D5 is a potent and selective diuretic drug that can effectively treat edema caused by various medical conditions. Its deuterated form provides additional benefits in terms of increased potency and selectivity. However, it should only be used under the guidance of a qualified healthcare professional and with close monitoring of its effects and potential side effects.

Related Compounds

N-Desbutyl-N-propyl Bumetanide-d5 | Bumetanide 3-(Butyl(nitroso)amino)-d5 | Desbutyl Bumetanide D5 |

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