3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt

3-Cysteinylacetaminophen-D5 (major) is a stable isotope labeled analog of acetaminophen, which is widely used as an analgesic and antipyretic agent. The compound is known to have a cysteine conjugation pathway in humans, which is important for its metabolism and elimination. This stable isotope labeled analog of acetaminophen can be used for pharmacokinetic and pharmacodynamic studies of the parent drug, by measuring the concentrations of the drug and its metabolites in biological samples. Trifluoroacetic acid salt is a commonly used salt in organic chemistry, and it is used as a reagent for peptide synthesis, and as a solvent for various organic reactions. It is a strong acid, and it is known to be corrosive to metals and tissues. It is also known to undergo rapid hydrolysis in water, which makes it unstable under certain conditions. The combination of 3-Cysteinylacetaminophen-D5 (major) with trifluoroacetic acid salt can be used for the extraction and purification of the labeled compound from biological matrices. The method involves the use of solid phase extraction cartridges, which are packed with a reversed-phase sorbent and trifluoroacetic acid salt. The use of trifluoroacetic acid salt helps to improve the recovery and purity of the labeled compound, by enhancing the ionization efficiency and suppressing the interference from other biological components. Overall, the combination of 3-Cysteinylacetaminophen-D5 (major) with trifluoroacetic acid salt can be a useful tool for the analysis of acetaminophen and its metabolites in biological samples.