9-cis-Retinol-d5

9-cis-Retinol-d5 is a derivative of vitamin A, which plays an important role in biological processes such as vision, cell growth, and differentiation. This compound is a stable isotope-labeled analog of 9-cis-retinol, which is a naturally occurring form of vitamin A. The d5 label refers to the presence of five deuterium atoms, which allows for precise measurement and tracking of the compound in biological systems. The primary usage of 9-cis-Retinol-d5 is in research and diagnostic applications, particularly in the study of vitamin A metabolism and signaling pathways. It can be used as a tracer molecule to investigate the absorption, transport, and metabolism of vitamin A in cells and tissues. Additionally, it can be used to study the activity of retinoid receptors, which are transcription factors that mediate the effects of vitamin A on gene expression. Chemically, 9-cis-Retinol-d5 is a yellow to orange crystalline powder that is soluble in organic solvents such as ethanol and chloroform. It has a molecular weight of 326.5 g/mol and a melting point of 62-64°C. In biological systems, it is metabolized to retinaldehyde and then to retinoic acid, which are the active forms of vitamin A that interact with retinoid receptors. Overall, 9-cis-Retinol-d5 is a valuable tool for investigating the role of vitamin A in biological processes and for understanding the mechanisms of retinoid signaling.