Amitriptyline N-Oxide-d6

Amitriptyline N-Oxide-d6, also known as 10,11-dihydro-5-(3-(dimethylamino)propyl)-5H-dibenzo[a,d]cyclohepten-5-ol N-oxide-d6, is a deuterated analogue of the antidepressant drug Amitriptyline N-Oxide. It is commonly used in scientific research as a stable isotope-labeled internal standard for quantification and analysis of Amitriptyline N-Oxide in biological samples. Amitriptyline N-Oxide-d6 is a tricyclic antidepressant that works by blocking the reuptake of norepinephrine and serotonin in the brain, resulting in increased levels of these neurotransmitters. It is also believed to have antagonistic effects on histamine and acetylcholine receptors. The drug is used to treat depression, anxiety disorders, and chronic pain conditions such as fibromyalgia and neuropathic pain. In terms of chemical information, Amitriptyline N-Oxide-d6 has a molecular formula of C20H20D6N2O2 and a molecular weight of 338.47 g/mol. It is a white crystalline powder that is soluble in water and ethanol. The deuterated version of the drug is used to ensure accurate and precise analysis of Amitriptyline N-Oxide levels in biological samples, as it minimizes the effects of isotopic fractionation during sample preparation and analysis. Overall, Amitriptyline N-Oxide-d6 is an important tool in scientific research for the quantification and analysis of Amitriptyline N-Oxide in biological samples, and it can provide valuable insights into the pharmacokinetics and pharmacodynamics of this tricyclic antidepressant drug.