7-Oxo Cholesterol-d7 3-Acetate

7-Oxo Cholesterol-d7 3-Acetate is a stable isotope-labeled analog of 7-Oxocholesterol, which is a cholesterol oxidation product that is formed under oxidative stress conditions. It is used in various biological and clinical research applications, such as in the study of lipid metabolism, atherosclerosis, and Alzheimer's disease. Chemically, 7-Oxo Cholesterol-d7 3-Acetate is a cholesterol derivative that contains seven deuterium atoms labeled at specific positions. The deuterium labeling improves the sensitivity and selectivity of analytical techniques such as mass spectrometry, which are used for the detection and quantification of 7-Oxo Cholesterol-d7 3-Acetate in biological samples. The compound is usually synthesized by chemical methods, using labeled precursors such as deuterated acetic anhydride and deuterated cholesterol. The final product is a white crystalline powder that is soluble in organic solvents such as chloroform, methanol, and ethanol. In research studies, 7-Oxo Cholesterol-d7 3-Acetate is used as an internal standard or a reference compound for the quantification of endogenous 7-Oxocholesterol levels in biological samples. It can also be used as a tool for investigating the metabolism and biochemistry of 7-Oxocholesterol, as well as its role in the pathogenesis of various diseases. Overall, 7-Oxo Cholesterol-d7 3-Acetate is a valuable research tool for studying the biological effects of cholesterol oxidation products and their impact on human health.