Amantadine-d15 Hydrochloride

Amantadine-d15 Hydrochloride is a deuterated form of the antiviral and antiparkinsonian drug Amantadine Hydrochloride. It is commonly used in scientific research as a stable isotope-labeled internal standard for the analysis of Amantadine in biological matrices. The chemical formula of Amantadine-d15 Hydrochloride is C10H18D15ClN and its molecular weight is 202.79 g/mol. It is a white to off-white crystalline powder that is soluble in water and slightly soluble in ethanol. Amantadine-d15 Hydrochloride acts by inhibiting the replication of influenza A virus and by stimulating the release of dopamine in the brain. It is also used in the treatment of Parkinson's disease as it helps to reduce the symptoms of tremors, rigidity, and bradykinesia. The recommended dosage of Amantadine-d15 Hydrochloride varies depending on the condition being treated and the patient's age and weight. The drug is usually administered orally and is well absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted in the urine. Like all medications, Amantadine-d15 Hydrochloride has potential side effects, which may include nausea, vomiting, insomnia, confusion, agitation, and hallucinations. It should not be used in patients with a history of allergy to Amantadine or with severe liver or kidney disease. In conclusion, Amantadine-d15 Hydrochloride is a useful drug for the treatment of influenza A virus and Parkinson's disease. Its stable isotope-labeled form is a valuable tool for research in pharmacokinetics, toxicology, and drug metabolism.