4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d5 O-b-D-Glucuronide (Major)(Mixture of Diastereomers)
| Product Name | 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d5 O-b-D-Glucuronide (Major)(Mixture of Diastereomers) |
|---|---|
| CAT No. | CS-T-98433 |
| CAS No. | Not Available |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 390.4 g/mol |
| Mol. For. | C16H18D5N3O8 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d5 O-b-D-Glucuronide (Major)(Mixture of Diastereomers) is a chemical compound that is commonly used in research studies related to the metabolism and elimination of tobacco-specific nitrosamines (TSNAs) in humans. This compound is a glucuronide conjugate of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), which is a potent carcinogenic substance found in tobacco smoke.
The chemical structure of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d5 O-b-D-Glucuronide (Major)(Mixture of Diastereomers) includes deuterium atoms, which are heavy isotopes of hydrogen. These deuterium atoms are used as tracers in metabolic studies to determine the fate of NNAL in the body. Specifically, the deuterium-labeled glucuronide is administered to study subjects, and the metabolites that are produced are analyzed using mass spectrometry techniques.
The glucuronidation of NNAL is an important metabolic pathway that results in the elimination of this carcinogenic substance from the body. The use of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d5 O-b-D-Glucuronide (Major)(Mixture of Diastereomers) in research studies allows for a better understanding of this process and the factors that influence the metabolism and elimination of TSNAs in humans. Ultimately, this knowledge can be used to develop strategies for reducing the harmful effects of tobacco smoke on human health.
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