(R,S)-N2-Nitroso-Anabasine-d4 N’-β-D-Glucuronide

(R,S)-N2-Nitroso-Anabasine-d4 N’-β-D-Glucuronide is a chemical compound that is used in various research and analytical applications. It is a stable isotopic labeled compound that is used as a reference standard in mass spectrometry-based methods for the analysis of tobacco-specific nitrosamines (TSNAs) in biological samples. The compound is a glucuronide conjugate of N2-nitrosoanabasine, a tobacco-specific nitrosamine that is a known carcinogen. The glucuronide conjugate is formed in the liver and excreted in the urine, making it a useful biomarker for exposure to TSNAs. Chemically, (R,S)-N2-Nitroso-Anabasine-d4 N’-β-D-Glucuronide is a complex molecule with a molecular formula of C26H28D4N3O11. It has a molecular weight of 603.5 g/mol and a melting point of 167-169°C. The compound is soluble in water and has a pale yellow color. In summary, (R,S)-N2-Nitroso-Anabasine-d4 N’-β-D-Glucuronide is a valuable tool for researchers and analytical chemists working in the field of tobacco research and exposure assessment. Its stable isotopic labeling and glucuronide conjugation make it a highly specific and sensitive biomarker for exposure to carcinogenic tobacco-specific nitrosamines.