Azelastine-d3
| Product Name | Azelastine-d3 |
|---|---|
| Alternate Names | Azelastine Stable Isotopes, Stable Isotopes of Azelastine |
| CAT No. | CS-TA-21031 |
| CAS No. | 758637-88-6 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 384.92 g/mol |
| Mol. For. | C22H21D3ClN3O |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Azelastine |
| Canonical Smiles | CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl |
| InchIKey | MBUVEWMHONZEQD-KQORAOOSSA-N |
| Inchl | InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3/i1+1D3 |
| IUPAC | 4-[(4-chlorophenyl)methyl]-2-[1-(trideuterio(113C)methyl)azepan-4-yl]phthalazin-1-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Azelastine-d3 is a stable isotope-labeled form of azelastine, a second-generation antihistamine drug used to treat allergic rhinitis and other allergic reactions. It is a nasal spray that works by blocking the action of histamine, a chemical released by the body during an allergic reaction that causes symptoms such as sneezing, itching, and runny nose.
Azelastine-d3 is typically administered as a 137 mcg spray, with each spray containing 0.137 mg of azelastine hydrochloride. It is a white to off-white powder that is soluble in water and has a molecular weight of 418.9 g/mol. The deuterium labeling in azelastine-d3 provides a unique chemical signature that can be used in pharmacokinetic and metabolic studies.
The drug is metabolized in the liver, with the primary metabolite being N-desmethylazelastine. The half-life of azelastine-d3 is approximately 22 hours, and it is excreted primarily in the urine.
As with all medications, azelastine-d3 may cause side effects such as drowsiness, headache, and nasal irritation. It is important to follow the dosage instructions provided by your healthcare provider and to avoid using it for longer than recommended. If you experience any severe side effects or allergic reactions, seek medical attention immediately.
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Related Compounds
Azelastine 13C,d3 | Azelastine D4 | Azelastine D4 Hydrochloride | N-desmethyl Azelastine D4 |