rac Benidipine-d5 Hydrochloride

Rac Benidipine-d5 Hydrochloride is a deuterated analogue of Benidipine Hydrochloride, a calcium channel blocker used in the treatment of hypertension. It is labeled with deuterium atoms at five positions in its molecular structure, which makes it a useful tool for studying drug metabolism, pharmacokinetics, and drug-drug interactions. The chemical structure of Rac Benidipine-d5 Hydrochloride is a dihydropyridine derivative, which inhibits calcium ion influx into vascular smooth muscle cells, resulting in vasodilation and reduction of blood pressure. It has a molecular weight of 495.07 g/mol and a chemical formula of C28H30D5ClN2O6. Rac Benidipine-d5 Hydrochloride is typically administered orally in the form of tablets or capsules. The recommended dosage for adults is 4-8 mg once daily, taken with or without food. The drug is metabolized in the liver and excreted primarily in the urine. There are some potential side effects associated with the use of Rac Benidipine-d5 Hydrochloride, including dizziness, headache, flushing, and edema. Patients with liver or kidney dysfunction should use caution when taking this medication, and it should not be used during pregnancy or breastfeeding. Overall, Rac Benidipine-d5 Hydrochloride is a useful tool for pharmacological research and has demonstrated efficacy in the treatment of hypertension. However, as with any medication, it should only be used under the guidance of a healthcare professional.