17a-Hydroxy Progesterone-d8

17a-Hydroxy Progesterone-d8, also known as 17α-hydroxyprogesterone-d8 or 17-OHP-d8, is a stable isotope-labeled derivative of the hormone 17α-hydroxyprogesterone (17-OHP). This compound is widely used in research and clinical laboratories for various applications, including tracer studies, pharmacokinetic analysis, and hormone replacement therapy. In terms of usage, 17a-Hydroxy Progesterone-d8 is primarily used as a stable isotope internal standard in mass spectrometry-based assays for the quantification of 17-OHP levels in biological samples. Its incorporation into the assay allows for accurate and reliable measurement of 17-OHP levels, which is essential for the diagnosis and management of disorders such as congenital adrenal hyperplasia and polycystic ovary syndrome. Chemically, 17a-Hydroxy Progesterone-d8 is a deuterated analog of 17-OHP, which means that eight hydrogen atoms in the molecule are replaced with deuterium atoms. This modification does not significantly alter the biological activity or properties of the compound and is used solely for analytical purposes. In summary, 17a-Hydroxy Progesterone-d8 is a useful tool for researchers and clinicians alike, providing accurate and reliable measurement of 17-OHP levels in biological samples. Its stable isotope labeling makes it an ideal internal standard in mass spectrometry-based assays, allowing for precise quantification of this important hormone.