7-Hydroxy Quetiapine-d8

7-Hydroxy Quetiapine-d8 is a deuterated form of 7-Hydroxy Quetiapine, which is an active metabolite of Quetiapine, an atypical antipsychotic drug. This deuterated form is used in scientific research and drug development due to its pharmacological properties. 7-Hydroxy Quetiapine-d8 is useful in the study of Quetiapine metabolism and drug-drug interactions. It is also used in the development of new drugs with improved pharmacokinetics and efficacy. This deuterated form is particularly useful in pharmacokinetic studies as it enables the quantification of the active metabolite, 7-Hydroxy Quetiapine, in biological samples, without interference from endogenous compounds. The chemical formula of 7-Hydroxy Quetiapine-d8 is C21H25D8N3O2S and its molecular weight is 381.6 g/mol. It is a deuterated form of 7-Hydroxy Quetiapine, which is a secondary amine with a pKa of 9.1. The deuterium labeling at position 8 of the molecule does not significantly affect its pharmacological activity but provides distinct advantages in drug development research. In conclusion, 7-Hydroxy Quetiapine-d8 is a useful tool in scientific research for drug metabolism studies and drug development. Its deuterium labeling provides a unique advantage in pharmacokinetic studies, allowing for more accurate quantification of the active metabolite.