Triclabendazole Sulfoxide

Product Name Triclabendazole Sulfoxide
Alternate Names Triclabendazole Impurities, Impurities of Triclabendazole
CAT No. CS-W-00076
CAS No. 100648-13-3
Category Impurities
Stock IN-Stock
Mol. Wt. 375.66 g/mol
Mol. For. C₁₄H₉Cl₃N₂O₂S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Triclabendazole
Canonical Smiles CS(=O)C1=NC2=CC(=C(C=C2N1)Cl)OC3=C(C(=CC=C3)Cl)Cl
InchIKey GABQPFWIQFRJSE-UHFFFAOYSA-N
Inchl InChI=1S/C14H9Cl3N2O2S/c1-22(20)14-18-9-5-8(16)12(6-10(9)19-14)21-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
IUPAC 6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfinyl-1H-benzimidazole
Controlled No
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Triclabendazole Sulfoxide is a chemical compound that is widely used in veterinary medicine for the treatment of liver fluke infections in animals. It is a derivative of Triclabendazole, which is an anthelmintic drug used to treat a variety of parasitic infections in livestock. Triclabendazole Sulfoxide is the active metabolite of Triclabendazole and is responsible for its anthelmintic properties. Triclabendazole Sulfoxide works by inhibiting the synthesis of tubulin, which is an essential component of microtubules in the liver fluke. This results in the disintegration of the parasite's cytoskeleton, which ultimately causes its death. The drug has been found to be effective against various species of liver flukes, including Fasciola hepatica and Fascioloides magna. The chemical formula of Triclabendazole Sulfoxide is C14H9Cl3N2O4S, and its molecular weight is 405.649 g/mol. It is a white to off-white crystalline powder that is sparingly soluble in water but soluble in organic solvents such as methanol and ethanol. The drug has a melting point of 196-198°C and a pKa value of 4.7. Triclabendazole Sulfoxide is mainly administered orally as a suspension or tablet. The recommended dosage varies depending on the animal species and the severity of the infection. The drug has a low toxicity profile and is generally well-tolerated by animals. However, like any medication, it may cause side effects such as vomiting, diarrhea, and abdominal pain in some cases. Therefore, it is important to follow the prescribed dosage and to consult a veterinarian before administering the drug.

Related Compounds

Triclabendazole EP impurity B | N-Nitroso Triclabendazole | Triclabendazole Sulfone |

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