5-Hydroxymebendazole D3

Product Name 5-Hydroxymebendazole D3
Alternate Names Mebendazole Stable Isotopes, Stable Isotopes of Mebendazole
CAT No. CS-W-00090
CAS No. 1173020-86-4
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Mebendazole
Canonical Smiles COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(C3=CC=CC=C3)O
InchIKey IIQKUGXEGMZCLE-UHFFFAOYSA-N
Inchl InChI=1S/C16H15N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9,14,20H,1H3,(H2,17,18,19,21)
IUPAC methyl N-[6-[hydroxy(phenyl)methyl]-1H-benzimidazol-2-yl]carbamate
Controlled No
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5-Hydroxymebendazole D3 is a deuterated analog of 5-hydroxymebendazole, which is a derivative of mebendazole that is commonly used in the treatment of parasitic infections. Mebendazole works by inhibiting the formation of microtubules in the parasite, thereby disrupting its metabolism and leading to its death. 5-Hydroxymebendazole D3 is a labeled compound that is used in pharmacokinetic analysis to determine the absorption, distribution, metabolism, and excretion of mebendazole in the body. The chemical formula of 5-Hydroxymebendazole D3 is C16H9D3N3O3, and its molecular weight is 307.33 g/mol. The compound has a melting point of 208-210°C and a purity of ≥98%. It is soluble in DMSO, ethanol, and methanol, and it should be stored at -20°C in a dry and dark place. The compound should also be handled with caution, as it may cause skin and eye irritation. In pharmacokinetic analysis, 5-Hydroxymebendazole D3 is administered to animals or humans, and its concentration in different tissues and fluids is measured over time. This information is used to determine the pharmacokinetic parameters of mebendazole, such as its bioavailability, half-life, clearance, and volume of distribution. This data is important in drug development, as it allows researchers to optimize the dosage and frequency of mebendazole administration in order to maximize its efficacy and minimize its toxicity. Overall, the use of 5-Hydroxymebendazole D3 is a valuable tool in the study of mebendazole and its pharmacokinetics.

Related Compounds

Mebendazole D3 | Mebendazole-amine-13C6 |

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