Threo Chloramphenicol D5

Product Name Threo Chloramphenicol D5
Alternate Names Chloramphenicol Stable Isotopes, Stable Isotopes of Chloramphenicol
CAT No. CS-W-00113
CAS No. 202480-68-0
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 328.16 g/mol
Mol. For. C₁₁D₅H₇Cl₂N₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Chloramphenicol
Purity 95%
Smileys C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
Canonical Smiles C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
InchIKey WIIZWVCIJKGZOK-CJBPKKHQSA-N
Inchl InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1/i1D,2D,3D,4D,9D
IUPAC 2,2-dichloro-N-[(1R,2R)-1-deuterio-1,3-dihydroxy-1-(2,3,5,6-tetradeuterio-4-nitrophenyl)propan-2-yl]acetamide
Controlled No
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Threo Chloramphenicol D5 is a stable isotope-labeled form of Chloramphenicol - a broad-spectrum antibiotic that is used to treat various bacterial infections. The "D5" in its name refers to the five deuterium atoms that have been substituted for the hydrogen atoms in the molecule. This substitution makes Threo Chloramphenicol D5 a valuable tool in pharmacokinetic and pharmacodynamic studies, as it allows researchers to track the drug's metabolism and distribution within the body. Threo Chloramphenicol D5 is typically administered orally or via injection, and its usage is primarily limited to treating serious bacterial infections such as meningitis, typhoid fever, and Rickettsial infections. The drug works by inhibiting bacterial protein synthesis, which prevents the bacteria from reproducing and eventually leads to their death. In terms of chemical information, Threo Chloramphenicol D5 has a molecular formula of C11H6D5Cl2NO2 and a molecular weight of 271.14 g/mol. It is a white crystalline powder that is stable under normal storage conditions. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 3-4 hours in humans. Overall, Threo Chloramphenicol D5 is a valuable tool in the fight against bacterial infections, and its stable isotope labeling makes it an important component of pharmacological research.

Related Compounds

Chloramphenicol D5 (phenyl-d4 acetamide-2-d) | Chloramphenicol 13C6 | Threo-Chloramphenicol-D6 | Chloramphenicol-d5 (100ug/mL in Acetonitrile) | Erythro Chloramphenicol D5 |

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