2-NP-SCA 13C,15N2

2-NP-SCA 13C,15N2 is a chemical compound that is primarily used in research applications. It is a labeled derivative of 2-nitrophenyl ethyl sulfide (NP-SCA), which is a reagent used for the detection of thiols and sulfhydryl groups in proteins. The labeling of 2-NP-SCA with carbon-13 and nitrogen-15 isotopes makes it a useful tool for studying protein structure and dynamics using nuclear magnetic resonance (NMR) spectroscopy. In NMR experiments, 2-NP-SCA 13C,15N2 can be used as a probe to measure the distance between the labeled site and other residues in the protein. This information can help researchers understand the conformational changes that occur in proteins during various biological processes. Additionally, the labeling of 2-NP-SCA with isotopes of carbon and nitrogen allows for better sensitivity and specificity in NMR experiments. Chemically, 2-NP-SCA 13C,15N2 is a yellow powder with a molecular weight of 238.17 g/mol. Its chemical formula is C8H5N2O4S*2(13C)*2(15N), indicating the presence of two carbon-13 and two nitrogen-15 isotopes in the molecule. This compound should be handled with care, as it is potentially hazardous and may cause skin and eye irritation. It should be stored in a cool, dry place away from sources of ignition and incompatible materials. Overall, 2-NP-SCA 13C,15N2 is a valuable tool for researchers interested in studying protein structure and dynamics.