Nalidixic acid D5

Nalidixic acid D5 is a deuterated derivative of nalidixic acid, which is a synthetic antibacterial agent that belongs to the class of quinolone antibiotics. Nalidixic acid D5 is used in clinical and research settings as an internal standard for the quantification of nalidixic acid in biological samples. The deuterated form of the drug is used to enhance the accuracy and precision of analytical methods, particularly in mass spectrometry-based techniques. Chemically, nalidixic acid D5 is a yellow crystalline powder that is soluble in water and ethanol. Its chemical formula is C12H6D5N2O3, and it has a molecular weight of 238.29 g/mol. The deuterated form of the drug is similar in structure to the non-deuterated form, but it contains five deuterium atoms that replace hydrogen atoms in the molecule. Nalidixic acid D5 works by inhibiting the activity of bacterial DNA gyrase, which is an enzyme that is essential for the replication and repair of bacterial DNA. By interfering with this process, nalidixic acid D5 can prevent the growth and proliferation of bacterial cells, making it an effective treatment for urinary tract infections and other bacterial infections. In conclusion, nalidixic acid D5 is a valuable tool for researchers and clinicians who require accurate and precise quantification of the drug in biological samples. Its chemical properties and mechanism of action make it an effective antibacterial agent for the treatment of a range of infections.