Parecoxib-D3
| Product Name | Parecoxib-D3 |
|---|---|
| Alternate Names | Parecoxib Stable Isotopes, Stable Isotopes of Parecoxib |
| CAT No. | CS-W-00380 |
| CAS No. | 198470-84-7(Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 373.44 g/mol |
| Mol. For. | C₁₉H₁₅D₃N₂O₄S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Parecoxib |
| Purity | Not less than 95 % |
| Smileys | CC1=C(C2=CC=C([S](NC(C([2H])([2H])C([2H])([2H])[2H])=O)(=O)=O)C=C2)C(C3=CC=CC=C3)=NO1 |
| Canonical Smiles | CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC=CC=C3)C |
| InchIKey | TZRHLKRLEZJVIJ-UHFFFAOYSA-N |
| Inchl | InChI=1S/C19H18N2O4S/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15/h4-12H,3H2,1-2H3,(H,21,22) |
| IUPAC | N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Parecoxib-D3 is a deuterated version of parecoxib, a non-steroidal anti-inflammatory drug (NSAID) that is commonly used for postoperative pain management. It works by inhibiting the enzyme cyclooxygenase-2 (COX-2), which is responsible for producing prostaglandins that cause inflammation and pain.
Parecoxib-D3 is often used in combination with other analgesics such as opioids or local anesthetics to provide multimodal pain relief. It is administered via intravenous injection and has a rapid onset of action, making it a useful option for acute pain management.
While parecoxib-D3 has not been extensively studied, the deuterated version may have advantages over the non-deuterated form. Deuterium is a stable isotope of hydrogen that can alter the pharmacokinetics and pharmacodynamics of a drug. It may increase the half-life of the drug, improve bioavailability, and decrease the likelihood of drug-drug interactions.
Like all medications, parecoxib-D3 has potential side effects. Common side effects include nausea, vomiting, and headache. It may also increase the risk of bleeding and should be used with caution in patients with a history of bleeding disorders or those taking anticoagulants. Parecoxib-D3 should not be used in patients with a known hypersensitivity to NSAIDs or in those with a history of asthma, urticaria, or other allergic reactions to aspirin or other NSAIDs.
Overall, parecoxib-D3 is a useful tool in the management of acute pain and can be a valuable addition to a multimodal analgesic regimen. As with all medications, it should be used judiciously and with close monitoring for potential adverse effects.
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Related Compounds
Parecoxib D5 |