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Captopril-d3

Chemical Name Captopril-d3
CAT No. CS-Y-00038
CAS Registry# 1356383-38-4
Status Prompt Dispatch
Category Stable Isotopes
Mol. Wt. 220.30 g/mol
Mol. For. C₉H₁₂D₃NO₃S
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information


Controlled No
Parent API Captopril
Therapeutic Anti-Hypertensives
Isotopic Enrichment Not Specified
Smileys C[C@@H](C(N1C([2H])([2H])CC[C@]1(C(O)=O)[2H])=O)CS
Canonical Smiles CC(CS)C(=O)N1CCCC1C(=O)O
InchIKey FAKRSMQSSFJEIM-SIHDFBQLSA-N
Inchl InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1/i4D2,7D
IUPAC (2S)-2,5,5-trideuterio-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Hazardous Yes


Usage and description


Captopril-d3 is a deuterated form of the drug Captopril, which is a medication used primarily to treat high blood pressure and heart failure. The deuterated form of the drug, Captopril-d3, contains three deuterium atoms, which are isotopes of hydrogen. This modification does not affect the drug’s therapeutic properties, but it can improve the drug’s stability and bioavailability. Captopril-d3 works by inhibiting the activity of an enzyme called angiotensin-converting enzyme (ACE), which plays a key role in regulating blood pressure. By inhibiting ACE, Captopril-d3 helps to dilate blood vessels, which reduces the amount of pressure on the heart and lowers blood pressure. The chemical formula of Captopril-d3 is C9H9D3N3O3S, and its molecular weight is 249.33 g/mol. The drug is available in tablet form, with each tablet typically containing 25 mg or 50 mg of Captopril-d3. Like most medications, Captopril-d3 may cause side effects, including dizziness, fatigue, nausea, and a dry cough. It is important to follow dosing instructions carefully and to speak with a healthcare provider if any side effects occur or if there are any concerns about the medication's usage. Overall, Captopril-d3 is a useful medication for managing high blood pressure and heart failure, and it has been shown to be safe and effective for many patients.

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