Olaparib D5
| Product Name | Olaparib D5 |
|---|---|
| Alternate Names | Olaparib Stable Isotopes, Stable Isotopes of Olaparib |
| CAT No. | CS-Y-00072 |
| CAS No. | 2143107-56-4 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 439.49 g/mol |
| Mol. For. | C₂₄H₁₈D₅FN₄O₃ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Olaparib |
| Purity | Not less than 90 % |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(C4([2H])C([2H])([2H])C4([2H])[2H])=O)CC3)=O)=C2)C5=C1C=CC=C5 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Olaparib D5 is a deuterated version of Olaparib, a potent inhibitor of Poly ADP-ribose polymerase (PARP) enzymes. Olaparib D5 is used as an internal standard in pharmacokinetic and pharmacodynamic studies to determine the concentration of Olaparib in biological samples. It is also used in clinical research to investigate the efficacy and safety of Olaparib in cancer treatment.
Olaparib D5 has the same chemical structure as Olaparib but with five deuterium atoms instead of hydrogen atoms. Deuterium is a stable isotope of hydrogen with a higher mass, making it useful as an internal standard to improve the accuracy and precision of mass spectroscopy-based assays. The deuterated version of Olaparib is chemically synthesized using complex organic chemistry techniques.
Olaparib D5 is a potent inhibitor of PARP enzymes, which play a critical role in DNA repair mechanisms. Cancer cells with mutations in DNA repair genes are more sensitive to PARP inhibition, making Olaparib D5 an effective targeted therapy for various types of cancer, including ovarian, breast, pancreatic, and prostate cancer.
In summary, Olaparib D5 is a deuterated version of Olaparib used as an internal standard for pharmacokinetic and pharmacodynamic studies. It is a potent inhibitor of PARP enzymes and is effective in treating various types of cancer.
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Related Compounds
Olaparib D4 | Olaparib D8 |