7-Ethyl-10-hydroxy camptothecin D4

7-Ethyl-10-hydroxy camptothecin D4 is a potent anti-cancer agent that is derived from a natural compound known as camptothecin. This compound is commonly used in the treatment of various types of cancer, including ovarian, lung, and colorectal cancers. The mechanism of action of 7-Ethyl-10-hydroxy camptothecin D4 is primarily through its ability to inhibit topoisomerase I, an enzyme that is critical for DNA replication and cell division. By inhibiting this enzyme, the compound prevents cancer cells from replicating and dividing, ultimately leading to their death. In terms of chemical information, 7-Ethyl-10-hydroxy camptothecin D4 is a semi-synthetic derivative of camptothecin. It has a molecular formula of C22H20N2O5 and a molecular weight of 400.41 g/mol. The compound is typically administered intravenously and has a half-life of approximately 2-3 hours. The dosage of 7-Ethyl-10-hydroxy camptothecin D4 is typically determined by the patient's body weight and the type of cancer being treated. While 7-Ethyl-10-hydroxy camptothecin D4 is a potent anti-cancer agent, it can also have side effects. Some of the most common side effects of this compound include nausea, vomiting, diarrhea, and fatigue. In rare cases, the compound can also cause more serious side effects such as bone marrow suppression and liver toxicity. As such, it is important for patients receiving this treatment to be closely monitored by their healthcare provider.