(S)-Lisinopril-d5 Sodium
| Product Name | (S)-Lisinopril-d5 Sodium |
|---|---|
| Alternate Names | Lisinopril Stable Isotopes, Stable Isotopes of Lisinopril |
| CAT No. | CS-ZG-51812 |
| CAS No. | 1356847-28-3 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 433.5 g/mol |
| Mol. For. | 433.5 g/mol |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Lisinopril |
| Smileys | C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.[Na] |
| Canonical Smiles | C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.[Na] |
| InchIKey | YIQJJOKNXHVFQD-DKOLOHLOSA-N |
| Inchl | InChI=1S/C21H31N3O5.Na/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);/t16-,17+,18+;/m0./s1/i1D,2D,3D,7D,8D; |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(S)-Lisinopril-d5 Sodium is a deuterated form of the angiotensin-converting enzyme (ACE) inhibitor Lisinopril. It is commonly used to treat high blood pressure, heart failure, and other cardiovascular conditions. The deuterium substitution in (S)-Lisinopril-d5 Sodium allows for more accurate analysis in clinical studies and research.
The mechanism of action of (S)-Lisinopril-d5 Sodium involves inhibition of ACE, which prevents the conversion of angiotensin I to angiotensin II. This leads to vasodilation, a decrease in blood pressure, and an improvement in cardiac function. The deuterated form of Lisinopril has similar efficacy to the non-deuterated form, but with improved sensitivity and specificity in pharmacokinetic and pharmacodynamic studies.
Chemically, (S)-Lisinopril-d5 Sodium is a white to off-white crystalline powder that is highly soluble in water. It has a molecular formula of C21H32D5N3O5Na and a molecular weight of 469.5 g/mol. The drug is administered orally and is rapidly absorbed, with peak plasma concentrations reached within 7 hours. The half-life of (S)-Lisinopril-d5 Sodium is approximately 12 hours, and it is primarily excreted in the urine.
Overall, (S)-Lisinopril-d5 Sodium is an important tool for researchers and clinicians studying the pharmacokinetics and pharmacodynamics of Lisinopril. Its deuterated form allows for more precise analysis and improved understanding of the drug's effects on the body.
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Related Compounds
N-Nitroso Lisinopril D5 TFA salt | N-Nitroso Lisinopril D5 | LISINOPRIL D5 DIHYDROCHLORIDE | Lisinopril D5 | Lisinopril 13C5,15N |