Baclofen-d4 (4-chlorophenyl-d4)

Product Name Baclofen-d4 (4-chlorophenyl-d4)
CAT No. CS-ZG-81264
CAS No. 1189938-30-4
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 217.69 g/mol
Mol. For. C₁₀H₈D₄ClNO₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys C1=CC(=CC=C1C(CC(=O)O)CN)Cl
Canonical Smiles C1=CC(=CC=C1C(CC(=O)O)CN)Cl
InchIKey KPYSYYIEGFHWSV-RHQRLBAQSA-N
Inchl InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/i1D,2D,3D,4D
IUPAC 4-amino-3-(4-chloro-2,3,5,6-tetradeuteriophenyl)butanoic acid
Controlled No
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Baclofen-d4 (4-chlorophenyl-d4) is a deuterated form of the muscle relaxant drug Baclofen. It is predominantly used in pharmacological and biochemical research as a stable isotope-labeled internal standard for the quantitative analysis of Baclofen in biological samples. Baclofen-d4 (4-chlorophenyl-d4) is a derivative of gamma-aminobutyric acid (GABA) that acts on the GABA-B receptors in the central nervous system, leading to muscle relaxation and reduction in spasticity. It is commonly prescribed for the treatment of spasticity associated with multiple sclerosis, spinal cord injury, and cerebral palsy. In terms of chemical information, Baclofen-d4 (4-chlorophenyl-d4) has a molecular formula of C10H7ClD4NO2 and a molecular weight of 228.75 g/mol. It is a deuterated compound, meaning that it contains hydrogen atoms that have been replaced with heavier deuterium atoms. This modification enhances the molecule's stability and reduces the risk of isotope scrambling during sample preparation and analysis. Overall, Baclofen-d4 (4-chlorophenyl-d4) is a useful tool for researchers studying the pharmacokinetics, metabolism, and excretion of Baclofen in vivo. Its availability as a stable isotope-labeled internal standard ensures accurate and precise quantification of Baclofen levels in biological matrices, which is essential for evaluating the drug's efficacy and safety in clinical settings.

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