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LOXO-101 (ARRY-470)

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Basic Chemical Information

CAT No.# CS-AV-00094
Category Inhibitors
CAS 1223403-58-4
Stock Status
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Specification

Molecular Weight 428.44
Molecular Formula C21H22F2N6O2
Purity >98
References Julia Haas, Steven W. Andrews, Yutong Jiang, Gan Zhang, Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors and their preparation and use in the treatment of diseases. WO2010048314 (2010).
Smileys O=C(N1CC[C@@H](C1)O)NC2=C3N=C(N4CCC[C@@H]4C5=CC(F)=CC=C5F)C=CN3N=C2

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(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

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