Pyridomycin

METABOLITES

Product Details

CAT No.# CS-CM-00152
Category Metabolites
CAS 18791-21-4
Molecular Weight 540.56
Molecular Formula C27H32N4O8
Synonyms: N-((5R,6S,9S,10R,11R,Z)-2-(butan-2-ylidene)-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-(pyridin-3-ylmethyl)-1,4-dioxa-8-azacyclododecan-6-yl)-3-hydroxypicolinamide
Application Notes: pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria, originally isolated from Streptomyces abidoflavus by Umezawa group at the NIH Japan in 1953, and since isolated from different species and published under several names. The unusual 12-membered macrocyclic depsipeptide comprises three unique sub-units incorporating two substituted pyridines. Pyridomycin is thought to target NADH-dependent enoyl (acyl-carrier-protein) reductase InhA. Recent reports of activity against isoniazid-resistant mycobacteria has seen pyridomycin identified as a potential lead for new generation antibiotics.A new antibiotic, pyridomycin.
References: Shirude Pravin S., Madhavapeddi Prashanti, Naik Maruti, Murugan Kannan, Shinde Vikas, Nandishaiah Radha, Bhat Jyothi, Kumar Anupriya, Hameed Shahul, Holdgate Geoffrey, Davies Gareth, McMiken Helen, Hegde Naina, Ambady Anisha, Venkatraman Janani, Panda Man
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The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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3. Benidipine D7
4. Lauroside D
5. Triazolam 13C D3
6. Icatibant impurity 1
7. BISPHENOL AF (RING-13C12)
8. 0.1% TFA in Water ULC-MS
9. Metamizole EP Impurity C HCl
10. Silodosin Metabolite D4
11. Brivaracetam Carboxylic acid metabolite [UCB 42145]
12. Terbuthylazine D5
13. tibolone (848)
14. (Z)-Dimethylvinphos
15. Silodosin Metabolite
16. 2-Phenoxymethanesulfonanilide
17. Nimesulide EP Impurity A
18. Acetone HPLC
19. Nandrolone Decanoate EP impurity F
20. N-(4-Bromophenyl)-3-methyl-N-(m-tolyl)aniline




This page contains information about Pyridomycin Cas 18791-21-4 and its Metabolites.
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