1-(2'-Chloro-2'-deoxy-β-D-arabinofuranosyl)cytosine

FINE CHEMICALS

   
1-(2'-Chloro-2'-deoxy-β-D-arabinofuranosyl)cytosine belongs to the category of Fine Chemicals with CAS Registry No: 58461-30-6

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CAT No. CS-N-00141
Category Fine Chemicals
CAS 58461-30-6
Mol. Weight 261.662 g/mol
Mol. Formula C9H12ClN3O4
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More info about 1-(2'-Chloro-2'-deoxy-β-D-arabinofuranosyl)cytosine
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Synonyms 58461-30-6;AC1O57SO;1-(2-Chloro-2-deoxy-D-arabinofuranosyl)cytosine;2(1H)-Pyrimidinone, 4-amino-1-(2-chloro-2-deoxy-beta-D-arabinofuranosyl)-;4-Amino-1-(2-chloro-2-deoxy-.beta.-D-arabinofuranosyl)pyrimidin-2(1H)-one;4-amino-1-[(2R,3S,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Purity (%) >98%
Application Notes Clofarabine is a nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase- a (IC50s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC50 = 5 nM). 1 It induces apoptosis in primary chronic lymphocytic
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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