1-(2'-Chloro-2'-deoxy-β-D-arabinofuranosyl)cytosine

FINE CHEMICALS

Availability: Available - Dispatch by : 3-Dec-2019 5:00 PM

CAT No.	CS-N-00141
Category	Fine Chemicals
CAS	58461-30-6
Mol. Weight	261.66 mol/g
Mol. Formula	C₉H₁₂ClN₃O₄

Product Description

Stock Status	Available - Dispatch by : 3-Dec-2019 5:00 PM
Synonyms	58461-30-6;AC1O57SO;1-(2-Chloro-2-deoxy-D-arabinofuranosyl)cytosine;2(1H)-Pyrimidinone, 4-amino-1-(2-chloro-2-deoxy-beta-D-arabinofuranosyl)-;4-Amino-1-(2-chloro-2-deoxy-.beta.-D-arabinofuranosyl)pyrimidin-2(1H)-one;4-amino-1-[(2R,3S,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Purity (%)	>98%
Application Notes	Clofarabine is a nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase- a (IC50s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC50 = 5 nM). 1 It induces apoptosis in primary chronic lymphocytic
	View COA View MSDS
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy Quality Assurance ISO 9001:2005 OHSAS 18001:2007 ISO 14001:2005 NIST Calibrated

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