Desmethyl Bosentan
METABOLITES    
Availability: In-Stock
Dispatch to United States by: 23-Jan-2020 5:00 PM
CAT No. CS-O-07395
Category Metabolites
Parent API Bosentan
CAS 253688-61-8
Mol. Weight 537.59 g/mol
Mol. Formula C26H27N5O6S
View COA View MSDS
Product Description
Stock Status In-Stock
Dispatch to United States by: 23-Jan-2020 5:00 PM
Synonyms Bosentan O-Desmethyl Impurity ;4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide;4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634; Phenol Metabolite of Bosentan
Storage Conditions For long term store at 2-8°C for Longer duration, in a well closed container.
Purity (%) >98%
Solubility Methanol
Appearance Yellow solid
Application Notes A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Phenol Metabolite of Bosentan
References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
Pubchem Id 6426756
Smiles CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4O
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Bosentan
- Stable Isotopes of Bosentan
- Metabolites of Bosentan
- Impurities of Bosentan
- Glucuronides of Bosentan
- Intermediates of Bosentan

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c1
ISO 9001:2005
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c5
ISO 14001:2005
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ISO 17034:2016
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ISO/IEC 17025:2017
c5
NIST Calibrated


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