Desmethyl Bosentan

METABOLITES

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 5 MG 350.00  332.00 
   mg 
 10 MG 500.00  475.00 
   mg 
 20 MG 700.00  665.00 
   mg 

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Product Details

CAT No.# CS-O-07395
Category Metabolites
CAS 253688-61-8
Molecular Weight 537.59
Molecular Formula C26H27N5O6S
Stock Status: In-Stock
Purity: >98%
Solubility: Methanol
Appearance: Yellow solid
Synonyms: Bosentan O-Desmethyl Impurity ;4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide;4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634; Phenol Metabolite of Bosentan
Application Notes: A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. Phenol Metabolite of Bosentan
References: Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
Storage: 2-8°C
COA / MSDS:    View COA    MSDS    Enquire
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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4. Benidipine D7
5. Lauroside D
6. Triazolam 13C D3
7. Icatibant impurity 1
8. BISPHENOL AF (RING-13C12)
9. 0.1% TFA in Water ULC-MS
10. Metamizole EP Impurity C HCl
11. Silodosin Metabolite D4
12. Brivaracetam Carboxylic acid metabolite [UCB 42145]
13. Terbuthylazine D5
14. tibolone (848)
15. (Z)-Dimethylvinphos
16. Silodosin Metabolite
17. 2-Phenoxymethanesulfonanilide
18. Nimesulide EP Impurity A
19. Acetone HPLC
20. Nandrolone Decanoate EP impurity F


SMILES:
O=[S](NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC(C=CC=C3)=C3O)(C4=CC=C(C(C)(C)C)C=C4)=O



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