Hydroxy Bosentan
Availability: In-Stock
Dispatch by : 18-Nov-2019 5:00 PM
CAT No. CS-O-10316
Category Metabolites
Parent API Bosentan
CAS 253688-60-7
Mol. Weight 567.61 mol/g
Mol. Formula C27H29N5O7S
Product Description
Stock Status In-Stock
Dispatch by : 18-Nov-2019 5:00 PM
Synonyms 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide
Storage Conditions
Purity (%) 97.04
Melting Point (℃)128-132 
Solubility Methanol
Appearance White Solid
Application Notes The active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.
References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
Smileys COC1=C(C=CC=C1)OC(C(N[S](=O)(C2=CC=C(C(C)(C)CO)C=C2)=O)=NC(C3=NC=CC=N3)=N4)=C4OCCO
View COA View MSDS
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

Quality Assurance

ISO 9001:2005
OHSAS 18001:2007
ISO 14001:2005
NIST Calibrated
Related Results

- API Standards of Bosentan
- Stable Isotopes of Bosentan
- Metabolites of Bosentan
- Impurities of Bosentan
- Glucuronides of Bosentan
- Intermediates of Bosentan

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