Glutaminyl-Methionyl-Glutamyl-Glutamyl-Glutamyl-Alanyl-Valyl-Arginine Trifluoroacetate
Availability: Available - Dispatch to United States by : 27-Dec-2019 5:00 PM
CAT No. CS-O-13851
Category Metabolites
Parent API Exenatide
CAS 868249-03-0
Mol. Weight 1105.1 g/mol
Mol. Formula C41H67F3N12O18S
View COA View MSDS
Product Description
Stock Status Available - Dispatch to United States by : 27-Dec-2019 5:00 PM
Synonyms QMEEEAVR TFA; Gln-Met-Glu-Glu-Glu-Ala-Val-Arg TFA; (2S,5S,8S,11S,14S,17S)-11,14-bis(2-carboxyethyl)-17-((S)-2-((S)-2,5-diamino-5-oxopentanamido)-4-(methylthio)butanamido)-2-(3-guanidinopropyl)-5-isopropyl-8-methyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaicosane-1,20-dioic acid compound with 2,2,2-trifluoroacetic acid
Purity (%) >98%
Application Notes Glutaminyl-Methionyl-Glutamyl-Glutamyl-Glutamyl-Alanyl-Valyl-Arginine Trifluoroacetate is a metabolite from Exenatide trypsin (Exenatide Acetate, E957300) digestion. Exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor.
References Pugazhenthi, U. et al.: Diabetol., 53, 2357 (2010); Li, C. et al.: Bioche,. Biophys. Res. Comm., 400, 563 (2010); Lupi, R. et al.: Diab. Obes. Metab., 10, 515 (2008); Kim, T.H. et al.: Bioconj. Chem., 22, 625 (2011);
Smiles O=C(O)[C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](NC([C@@H](N)CCC(N)=O)=O)CCSC)=O)CCC(O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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Related Results

- API Standards of Exenatide
- Stable Isotopes of Exenatide
- Metabolites of Exenatide
- Impurities of Exenatide
- Glucuronides of Exenatide
- Intermediates of Exenatide

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